Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112829 | 0.76 | CA12 (0.36) | NPSR1TDP1THRBTSHRALDH1A1 | |
| SCHEMBL15136482 | 0.76 | MAPT (0.36) | NPSR1TDP1THRBTSHRALDH1A1 | |
| SCHEMBL28956318 | 0.75 | AKR1C1 (0.41) | NPSR1TDP1THRBTSHRALDH1A1 | |
| SCHEMBL11093099 | 0.72 | CTSD (0.34) | NPSR1TDP1TSHRALDH1A1CES1 | |
| SCHEMBL9469517 | 0.67 | PKM (0.38) | TSHRALDH1A1L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL966475 | 0.67 | SMN1; SMN2 (0.34) | TSHRALDH1A1CES2CES1NAPRT | |
| SCHEMBL6688749 | 0.67 | THRB (0.31) | NPSR1TDP1THRBTSHRALDH1A1 | |
| SCHEMBL9513409 | 0.67 | PKM (0.38) | TSHRALOX15SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL11884645 | 0.67 | L3MBTL1 (0.33) | NPSR1TSHRALDH1A1CES2CES1 | |
| SCHEMBL3356415 | 0.67 | KDM4E (0.32) | TDP1TSHRALDH1A1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751081-B2 | Self-regenerating antioxidant catalysts and methods of using the same | CLEMSON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160151773-A1 | SELF-REGENERATING ANTIOXIDANT CATALYSTS AND METHODS OF USING THE SAME | CLEMSON UNIVERSITY | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160151773-A1 | SELF-REGENERATING ANTIOXIDANT CATALYSTS AND METHODS OF USING THE SAME | SOD1, CAT, GPX4 | NPSR1 3748/4885TDP1 688/4885THRB 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.