Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | AOC2 | O75106 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176045 | 0.76 | HPGD (0.58) | HPGDTSHRGABRA1GABRB2NFKB1 | |
| SCHEMBL9390060 | 0.73 | CHRM2 (0.40) | HPGDTSHRGABRA1GABRB2AOC2 | |
| SCHEMBL5846867 | 0.72 | HPGD (0.54) | HPGDTSHRGABRA1GABRB2NFKB1 | |
| SCHEMBL3519014 | 0.72 | HPGD (0.54) | HPGDTSHRGABRA1GABRB2NFKB1 | |
| SCHEMBL5846876 | 0.72 | HPGD (0.54) | HPGDTSHRGABRA1GABRB2NFKB1 | |
| SCHEMBL2977413 | 0.71 | KDM4E (0.40) | HPGDGABRA1GABRB2MAOBDYRK1A | |
| SCHEMBL3780431 | 0.70 | GABRA1 (0.41) | HPGDTSHRGABRA1GABRB2NFKB1 | |
| SCHEMBL2152568 | 0.69 | HPGD (0.58) | HPGDTSHRGABRA1GABRB2NFKB1 | |
| SCHEMBL9374719 | 0.69 | SIGMAR1 (0.44) | HPGDTSHRGABRA1GABRB2AOC2 | |
| SCHEMBL27730852 | 0.69 | HPGD (0.61) | HPGDTSHRGABRA1GABRB2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056758-A1 | QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-05-20 | — | — | WO | disclosed |