SCHEMBL3356481

SCHEMBL3356481

CC(C)(c1ccccc1)c1ccc(Nc2cccc3ccccc23)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.66
ALDH1A1 P00352 3/20 0.66
HPGD P15428 2/20 0.66
ATM Q13315 2/20 0.66
CDC25B P30305 2/20 0.66
TP53 P04637 1/20 0.66
ALOX15 P16050 1/20 0.66
TSHR P16473 1/20 0.66
HSD17B10 Q99714 1/20 0.66
RAB9A P51151 3/20 0.58
KDM4E B2RXH2 2/20 0.52
MEN1 O00255 2/20 0.52
GAA P10253 2/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
GLA P06280 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
FADS1 O60427 1/20 0.47
NR3C2 P08235 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30012692 0.87 ALDH1A1 (0.65) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL4238282 0.87 ALDH1A1 (0.65) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL7524777 0.83 ALDH1A1 (0.44) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL29619354 0.82 HSD17B10 (0.87) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL651572 0.82 HSD17B10 (0.87) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL9472954 0.81 CDC25B (0.57) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL8373131 0.81 ALDH1A1 (0.61) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL4797443 0.81 ALDH1A1 (0.92) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL29609502 0.81 ALDH1A1 (0.92) CYP3A4ALDH1A1HPGDATMCDC25B
SCHEMBL29350230 0.80 ALDH1A1 (1.00) CYP3A4ALDH1A1HPGDATMCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4122021-A PHENYLATED NAPHTHALAMINES, SULFOXIDES UNIROYAL, INC. (US) 1978-10-24 US claimed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US claimed
US-8030259-B2 Antioxidant; heat resistance; photostability mixture; stabilization of material CIBA SPECIALITY CHEMICALS CORP. (US) 2011-10-04 US disclosed
US-8030259-B2 Antioxidant; heat resistance; photostability mixture; stabilization of material CIBA SPECIALITY CHEMICALS CORP. (US) 2011-10-04 US disclosed
US-20100058837-A1 DEVICE HAVING MULTIPLE LIGHT SOURCES AND METHODS OF USE THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. 2010-03-11 US disclosed
US-7673497-B2 System, methods, and compositions for detecting and inhibiting leaks in transmission systems IDQ OPERATING, INC. (US) 2010-03-09 US disclosed
US-7565829-B2 System, methods, and compositions for detecting and inhibiting leaks in steering systems E.F. Products (US) 2009-07-28 US disclosed
US-7565830-B2 System, methods, and compositions for detecting and inhibiting leaks in engine oil systems E.F. Products (US) 2009-07-28 US disclosed
EP-2055763-A1 Lubricating oil composition Shell Internationale Research Maatschappij B.V. (NL) 2009-05-06 EP disclosed
US-20080274925-A1 Alkylated Pana and Dpa Compositions CIBA SPECIALTY CHEMICALS CORP. 2008-11-06 US disclosed
US-20080274925-A1 Alkylated Pana and Dpa Compositions CIBA SPECIALTY CHEMICALS CORP. 2008-11-06 US disclosed
US-20070087946-A1 System, methods, and compositions for detecting and inhibiting leaks in steering systems THE ARMOR ALL/STP PRODUCTS COMPANY 2007-04-19 US disclosed
US-20070084269-A1 System, methods, and compositions for detecting and inhibiting leaks in engine oil systems THE ARMOR ALL/STP PRODUCTS COMPANY 2007-04-19 US disclosed
US-20070087945-A1 introducingt into system one or more transmission system sealants, one or more fluids compatible with transmission system lubricant, and one or more light activated compounds, wherein sealants inhibit leaks of transmission system during use, directing activating light toward system JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2007-04-19 US disclosed
EP-0780340-B1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORP (US) 2002-03-20 EP disclosed
US-20020007663-A1 Method of introducing an in situant into a vapor compression system, especially useful for leak detection, as well as an apparatus for leak detection and a composition useful for leak detection MAINSTREAM ENGINEERING CORPORATION 2002-01-24 US disclosed
US-6327897-B1 Method of introducing an in situant into a vapor compression system, especially useful for leak detection, as well as an apparatus for leak detection and a composition useful for leak detection MAINSTREAM ENGINEERING CORPORATION 2001-12-11 US disclosed
US-6170320-B1 Method of introducing an additive into a fluid system, especially useful for leak detection, as well as an apparatus for leak detection and a composition useful for leak detection MAINSTREAM ENGINEERING CORPORATION 2001-01-09 US disclosed
US-4110234-A PHENYLATED NAPHTHYLAMINE, SULFUR COMPOUND, METAL UNIROYAL, INC. (US) 1978-08-29 US disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed