SCHEMBL3356629

SCHEMBL3356629

CCO[Si](CCCCC(=O)OC(=O)CCCC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
DGKA P23743 1/20 0.35
CYP1A2 P05177 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 4/20 0.33
LMNA P02545 3/20 0.33
PAM P19021 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.31
CYP3A4 P08684 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DNM1 Q05193 1/20 0.30
NAAA Q02083 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3356634 0.91 ALDH1A1 (0.34) ALDH1A1DGKACYP1A2GAATSHR
SCHEMBL11878749 0.86 CYP1A2 (0.52) ALDH1A1DGKACYP1A2GAATSHR
SCHEMBL29259384 0.85 TSHR (0.50) ALDH1A1DGKAGAATSHRLMNA
SCHEMBL19770563 0.85 TSHR (0.50) ALDH1A1DGKAGAATSHRLMNA
SCHEMBL9138936 0.85 TSHR (0.50) ALDH1A1DGKAGAATSHRLMNA
SCHEMBL22398870 0.82 DGKA (0.35) ALDH1A1DGKACYP1A2GAATSHR
SCHEMBL2209569 0.82 AKR1B1 (0.48) ALDH1A1TSHRLMNAMAPTTDP1
SCHEMBL20390493 0.82 PAOX (0.40) ALDH1A1GAALMNATDP1HSD17B10
SCHEMBL4528611 0.80 GPR84 (0.50) ALDH1A1TSHRLMNAMAPTTDP1
SCHEMBL4532402 0.80 GPR84 (0.50) ALDH1A1TSHRLMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140206793-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-24 US disclosed
US-20140187707-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-03 US disclosed
EP-2749591-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-07-02 EP disclosed
EP-2740759-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-06-11 EP disclosed
EP-2177562-B1 Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
EP-2184318-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2014-03-19 EP disclosed
US-8431644-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-04-30 US disclosed
EP-2182028-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-12-12 EP disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed