Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 13/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253756 | 0.90 | HTR7 (0.71) | HTR7KMT2AKCNJ1ALDH1A1MEN1 | |
| SCHEMBL12857203 | 0.89 | HTR7 (0.69) | HTR7KMT2AKCNJ1ALDH1A1MEN1 | |
| SCHEMBL7806987 | 0.87 | HTR7 (0.60) | HTR7KCNJ1ALDH1A1 | |
| SCHEMBL1122811 | 0.87 | HTR7 (0.64) | HTR7KMT2AKCNJ1ALDH1A1MEN1 | |
| SCHEMBL7804965 | 0.85 | SIGMAR1 (0.62) | HTR7P2RX7KCNJ1 | |
| SCHEMBL29167527 | 0.82 | HTR7 (0.74) | HTR7KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL1121934 | 0.82 | HTR7 (0.82) | HTR7KMT2AALDH1A1MEN1 | |
| SCHEMBL17023236 | 0.82 | HTR7 (0.59) | HTR7 | |
| SCHEMBL1121912 | 0.81 | HTR7 (0.80) | HTR7KMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL4525372 | 0.81 | HTR7 (0.80) | HTR7KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |