Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603977 | 0.83 | GPR119 (0.52) | ALDH1A1NPC1RAB9APIK3CDPIK3CA | |
| SCHEMBL5560085 | 0.81 | HTR2B (0.52) | PIK3CDPIK3CAKDM4EHTR2BMEN1 | |
| SCHEMBL18141879 | 0.71 | MAPT (0.52) | ALDH1A1NPC1RAB9ANOS1NOS2 | |
| SCHEMBL1604665 | 0.71 | MEN1 (0.61) | RAB9ASMN1; SMN2HTTHTR2BMEN1 | |
| SCHEMBL5850886 | 0.70 | MEN1 (0.64) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL1604853 | 0.70 | MEN1 (0.49) | ALDH1A1NPC1RAB9APIK3CDPIK3CA | |
| SCHEMBL1604780 | 0.69 | HTR2B (0.65) | RAB9ASMN1; SMN2LMNAHTTHTR2B | |
| SCHEMBL3345087 | 0.69 | LMNA (0.59) | ALDH1A1HSD17B10NPC1HPGDRAB9A | |
| SCHEMBL1605075 | 0.69 | MEN1 (0.63) | ALDH1A1HSD17B10KDM4ELMNAMAPT | |
| SCHEMBL29017063 | 0.69 | PIK3CD (0.64) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-B1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2010-08-11 | — | — | EP | disclosed |