Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603977 | 0.84 | GPR119 (0.52) | HTR2BPIK3CDPIK3CACNR1CNR2 | |
| SCHEMBL3356965 | 0.81 | ALDH1A1 (0.49) | HTR2BMEN1PIK3CDPIK3CAKMT2A | |
| SCHEMBL1604873 | 0.81 | MEN1 (0.53) | MEN1PIK3CDPIK3CAKMT2AKDM4E | |
| SCHEMBL29017074 | 0.80 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1605075 | 0.78 | MEN1 (0.63) | HTR2BMEN1KMT2AKDM4EIRAK4 | |
| SCHEMBL1605161 | 0.77 | MEN1 (0.64) | HTR2BMEN1KMT2ACNR1CNR2 | |
| SCHEMBL5310731 | 0.77 | CNR1 (0.64) | CNR1CNR2IRAK4 | |
| Hydrochloric Acid SCHEMBL1604783 | 0.77 | MEN1 (0.62) | HTR2BMEN1KMT2AKDM4EIRAK4 | |
| SCHEMBL1604780 | 0.76 | HTR2B (0.65) | HTR2BMEN1KMT2A | |
| SCHEMBL3358824 | 0.75 | MEN1 (0.54) | HTR2BMEN1KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |