Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537329 | 0.81 | CNR2 (0.44) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3353157 | 0.79 | MAPT (0.55) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9400555 | 0.75 | KDM4E (0.46) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL3357664 | 0.75 | HRH3 (0.47) | ALDH1A1HSD17B10KDM4EMAPTCYP2A13 | |
| SCHEMBL30409773 | 0.74 | CNR1 (0.47) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9400579 | 0.74 | KDM4E (0.45) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL23606081 | 0.73 | HRH3 (0.47) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL3351981 | 0.72 | ICMT (0.55) | CNR2CNR1HSD17B10KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1391137 | 0.70 | POLB (0.56) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL3399817 | 0.70 | CYP2A13 (0.61) | CNR2CNR1KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |