Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357288 | 0.79 | CNR2 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13537329 | 0.79 | CNR2 (0.44) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3358883 | 0.78 | CTSB (0.59) | MAPTCTSBALDH1A1LMNAKCNJ1 | |
| SCHEMBL9400567 | 0.77 | MAPT (0.67) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28753894 | 0.75 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3357604 | 0.75 | CTSB (0.56) | MAPTCTSBALDH1A1LMNAKCNJ1 | |
| SCHEMBL17979926 | 0.74 | CTSB (0.71) | MAPTCTSBALDH1A1LMNAKCNJ1 | |
| SCHEMBL2573641 | 0.74 | CTSB (0.67) | MAPTCTSBALDH1A1LMNAKCNJ1 | |
| SCHEMBL9400698 | 0.73 | MAPT (0.60) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3357652 | 0.73 | CTSB (0.59) | MAPTCTSBALDH1A1LMNAKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |