Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352674 | 0.86 | CDK2 (0.44) | KMT2AMEN1CDK2MAPTALDH1A1 | |
| SCHEMBL7508094 | 0.81 | CDK2 (0.46) | KMT2AMEN1CDK2MAPTLMNA | |
| SCHEMBL6488744 | 0.79 | MAPT (0.49) | CDK2MAPTLMNA | |
| SCHEMBL5327849 | 0.79 | CDK2 (0.56) | KMT2AMEN1CDK2MAPTALDH1A1 | |
| SCHEMBL8188575 | 0.76 | CDK2 (0.36) | KMT2AMEN1CDK2MAPTLMNA | |
| SCHEMBL3358211 | 0.76 | MAPT (0.47) | KMT2AMEN1CDK2MAPTAR | |
| SCHEMBL29263665 | 0.76 | NR4A2 (0.59) | KMT2AMEN1CDK2MAPTLMNA | |
| SCHEMBL27709706 | 0.76 | CDK2 (0.46) | KMT2AMEN1CDK2MAPTLMNA | |
| SCHEMBL3351542 | 0.75 | ALDH1A1 (0.46) | KMT2AMEN1CDK2MAPTAR | |
| SCHEMBL3353911 | 0.75 | ALDH1A1 (0.45) | KMT2AMEN1CDK2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |