Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | PKLR | P30613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359227 | 0.85 | SYK (0.33) | CYP3A4SCN9ASCN10A | |
| SCHEMBL3242322 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL3247384 | 0.76 | BUB1 (0.33) | — | |
| SCHEMBL3248775 | 0.76 | SCN9A (0.33) | CYP3A4SCN9ASCN10A | |
| SCHEMBL3357372 | 0.76 | TDP2 (0.35) | TDP2PKLR | |
| SCHEMBL3244383 | 0.65 | MEN1 (0.30) | — | |
| SCHEMBL21178384 | 0.64 | GAA (0.39) | — | |
| SCHEMBL6242484 | 0.63 | KAT6A (0.47) | CYP3A4TDP2 | |
| SCHEMBL6644445 | 0.62 | DRD2 (0.52) | — | |
| SCHEMBL3532957 | 0.62 | TAS1R3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100125081-A1 | NEW COMPOUNDS 574 | ASTRAZENECA AB (SE) | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125081-A1 | NEW COMPOUNDS 574 | PSEN1, PSEN2, BACE1 | CYP3A4 3992/4885SCN9A 3075/4885SCN10A 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.