Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357437 | 0.90 | PDE7A (0.58) | PDE7AMAPTLMNASMN1; SMN2SLC6A4 | |
| SCHEMBL866726 | 0.73 | PDE7A (0.86) | PDE7AMAPTLMNASMN1; SMN2SLC6A4 | |
| SCHEMBL30605799 | 0.73 | PDE7A (0.86) | PDE7AMAPTLMNASMN1; SMN2SLC6A4 | |
| SCHEMBL30605781 | 0.65 | MAPT (0.79) | PDE7AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL864952 | 0.65 | MAPT (0.79) | PDE7AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL8095611 | 0.61 | PDE7A (1.00) | PDE7AMAPTLMNASMN1; SMN2SLC6A4 | |
| SCHEMBL7607819 | 0.60 | PDE7A (1.00) | PDE7AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL1455439 | 0.60 | PDE7A (0.74) | PDE7AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL864911 | 0.59 | IDO1 (0.47) | MAPTPPARGALDH1A1 | |
| SCHEMBL5141111 | 0.59 | POLB (0.38) | MAPTLMNASMN1; SMN2SLC6A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152660-A2 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | Rolic AG (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008145225-A2 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | ROLIC AG (CH) | 2008-12-04 | — | — | WO | disclosed |