Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336016 | 0.84 | CASP1 (0.39) | GAALMNAALDH1A1L3MBTL1 | |
| SCHEMBL4102918 | 0.81 | GAA (0.44) | MEN1KMT2ACES2CES1GAA | |
| SCHEMBL28573250 | 0.80 | HTT (0.44) | KMT2ACYP3A4GAAALDH1A1 | |
| SCHEMBL28573252 | 0.80 | HTT (0.44) | KMT2ACYP3A4GAAALDH1A1 | |
| SCHEMBL4178016 | 0.78 | HTT (0.44) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19658634 | 0.73 | L3MBTL1 (0.50) | MEN1KMT2ACES2CES1GAA | |
| SCHEMBL13050559 | 0.72 | KMT2A (0.36) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13584745 | 0.71 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL5021257 | 0.71 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL4543253 | 0.71 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | disclosed |