Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172184 | 0.74 | KDM4E (0.39) | HTR2CCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL25346159 | 0.73 | CSNK2A2 (0.37) | HTR2CCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL31155205 | 0.73 | CSNK2A2 (0.37) | HTR2CCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL20745977 | 0.70 | CSNK2A2 (0.35) | HTR2CCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL6240033 | 0.70 | CSNK2A2 (0.35) | HTR2CCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL5198824 | 0.70 | SMN1; SMN2 (0.36) | HTR2CCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL7260119 | 0.68 | MAOA (0.37) | NOS3NOS1NOS2ESR1HTR2C | |
| SCHEMBL24799425 | 0.67 | NOS2 (0.48) | NOS3NOS1NOS2ESR1IKBKB | |
| SCHEMBL4769008 | 0.64 | KDM4E (0.46) | KDM4EMAPT | |
| SCHEMBL4773700 | 0.64 | MAPT (0.39) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-B1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2010-08-11 | — | — | EP | disclosed |