Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610232 | 0.85 | SIGMAR1 (0.52) | HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL14305457 | 0.84 | HRH3 (0.67) | HRH3ACHEHTR7 | |
| SCHEMBL3356655 | 0.82 | HRH3 (0.47) | HRH3ACHEL3MBTL1KDM4E | |
| SCHEMBL6419877 | 0.82 | HRH3 (0.75) | HRH3ACHESIGMAR1SPHK1L3MBTL1 | |
| SCHEMBL613544 | 0.82 | HRH3 (0.61) | HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL3359369 | 0.81 | HRH3 (0.46) | HRH3ACHESIGMAR1KDM4E | |
| SCHEMBL3356095 | 0.81 | L3MBTL3 (0.62) | HRH3L3MBTL1 | |
| SCHEMBL23711032 | 0.80 | HRH3 (0.77) | HRH3ACHESIGMAR1SPHK1 | |
| SCHEMBL3357116 | 0.80 | HRH3 (0.65) | HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL3356355 | 0.80 | HRH3 (0.65) | HRH3SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177562-B1 | Polymer, rubber composition and tire using the same | SUMITOMO RUBBER IND (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2184318-B1 | Rubber composition and tire | SUMITOMO RUBBER IND (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-8431644-B2 | Rubber composition and tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2013-04-30 | — | — | US | disclosed |
| EP-2182028-B1 | Rubber composition and tire | SUMITOMO RUBBER IND (JP) | 2012-12-12 | — | — | EP | disclosed |
| EP-2184318-A2 | Rubber composition and tire | Sumitomo Rubber Industries, Ltd. (JP) | 2010-05-12 | — | — | EP | disclosed |
| EP-2182028-A1 | Rubber composition and tire | Sumitomo Rubber Industries, Ltd. (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20100105826-A1 | RUBBER COMPOSITION AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100099810-A1 | POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100099795-A1 | RUBBER COMPOSITION AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2177562-A2 | Polymer, rubber composition and tire using the same | Sumitomo Rubber Industries, Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |