SCHEMBL3356095

SCHEMBL3356095

C=Cc1ccc(CCN2CCC(N3CCCC3)CC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 15/20 0.62
L3MBTL1 Q9Y468 12/20 0.62
TP53BP1 Q12888 2/20 0.62
MBTD1 Q05BQ5 2/20 0.62
MAPT P10636 1/20 0.53
HRH3 Q9Y5N1 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360228 0.99 L3MBTL3 (0.63) L3MBTL3L3MBTL1TP53BP1MBTD1MAPT
SCHEMBL613544 0.85 HRH3 (0.61) L3MBTL3L3MBTL1TP53BP1MBTD1HRH3
SCHEMBL817494 0.83 HRH3 (0.65) L3MBTL3L3MBTL1MBTD1HRH3
SCHEMBL3357116 0.83 HRH3 (0.65) L3MBTL3L3MBTL1MBTD1HRH3
SCHEMBL3356355 0.83 HRH3 (0.65) L3MBTL3L3MBTL1MBTD1HRH3
SCHEMBL611191 0.83 HRH3 (0.65) L3MBTL3L3MBTL1MBTD1HRH3
SCHEMBL27802901 0.82 DRD2 (0.49) L3MBTL3L3MBTL1TP53BP1MBTD1MAPT
SCHEMBL27879037 0.81 HRH3 (0.56) L3MBTL3L3MBTL1MBTD1HRH3
SCHEMBL610232 0.81 SIGMAR1 (0.52) L3MBTL3L3MBTL1MBTD1HRH3
SCHEMBL3357901 0.81 HRH3 (0.69) L3MBTL1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2177562-B1 Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
EP-2184318-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2014-03-19 EP disclosed
CN-101724185-B Rubber composition and tire SUMITOMO RUBBER IND 2013-10-23 CN disclosed
CN-101724184-B Rubber composition and tire SUMITOMO RUBBER IND 2013-05-01 CN disclosed
US-8431644-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-04-30 US disclosed
EP-2182028-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-12-12 EP disclosed
CN-101724127-A Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND 2010-06-09 CN disclosed
CN-101724184-A Rubber composition and tire SUMITOMO RUBBER IND 2010-06-09 CN disclosed
CN-101724185-A Rubber composition and tire SUMITOMO RUBBER IND 2010-06-09 CN disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed