Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 6/20 | 0.45 |
| ▸ | THRB | P10828 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356622 | 1.00 | SIGMAR1 (0.50) | SIGMAR1EBPTHRATHRBKCNH2 | |
| SCHEMBL3359358 | 0.94 | SIGMAR1 (0.45) | SIGMAR1EBPTHRATHRBKCNH2 | |
| SCHEMBL3356681 | 0.87 | SIGMAR1 (0.45) | SIGMAR1THRATHRBKCNH2MEN1 | |
| SCHEMBL3354433 | 0.86 | DRD2 (0.50) | THRATHRBKCNH2MEN1KMT2A | |
| SCHEMBL3359329 | 0.86 | DRD2 (0.50) | THRATHRBKCNH2MEN1KMT2A | |
| SCHEMBL10533299 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2MEN1KMT2ACA1 | |
| SCHEMBL27298978 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2MEN1KMT2ACA1 | |
| SCHEMBL15829790 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2MEN1KMT2ACA1 | |
| SCHEMBL3356607 | 0.86 | DRD2 (0.50) | THRATHRBKCNH2MEN1KMT2A | |
| SCHEMBL17488865 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177562-B1 | Polymer, rubber composition and tire using the same | SUMITOMO RUBBER IND (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2184318-B1 | Rubber composition and tire | SUMITOMO RUBBER IND (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-8431644-B2 | Rubber composition and tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2013-04-30 | — | — | US | disclosed |
| EP-2182028-B1 | Rubber composition and tire | SUMITOMO RUBBER IND (JP) | 2012-12-12 | — | — | EP | disclosed |
| CN-101724185-A | Rubber composition and tire | SUMITOMO RUBBER IND | 2010-06-09 | — | — | CN | disclosed |
| CN-101724184-A | Rubber composition and tire | SUMITOMO RUBBER IND | 2010-06-09 | — | — | CN | disclosed |
| EP-2184318-A2 | Rubber composition and tire | Sumitomo Rubber Industries, Ltd. (JP) | 2010-05-12 | — | — | EP | disclosed |
| EP-2182028-A1 | Rubber composition and tire | Sumitomo Rubber Industries, Ltd. (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20100105826-A1 | RUBBER COMPOSITION AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100099810-A1 | POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100099795-A1 | RUBBER COMPOSITION AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2177562-A2 | Polymer, rubber composition and tire using the same | Sumitomo Rubber Industries, Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |