Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359358 | 0.90 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3358825 | 0.87 | ALDH1A1 (0.41) | SIGMAR1HRH3ALDH1A1KCNH2CYP1A2 | |
| SCHEMBL3358150 | 0.87 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1KCNH2CYP3A4THRA | |
| SCHEMBL3356622 | 0.87 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1KCNH2CYP3A4THRA | |
| SCHEMBL3360067 | 0.86 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1KCNH2TAAR1 | |
| SCHEMBL11442805 | 0.84 | CARM1 (0.41) | SIGMAR1HRH3ALDH1A1KCNH2CYP1A2 | |
| SCHEMBL18868380 | 0.84 | PYCR1 (0.43) | SIGMAR1HRH3ALDH1A1MEN1MAPT | |
| SCHEMBL610732 | 0.84 | DRD2 (0.50) | HRH3ALDH1A1CYP3A4CYP2D6PMP22 | |
| SCHEMBL213342 | 0.81 | HRH3 (0.59) | SIGMAR1HRH3ALDH1A1KCNH2TAAR1 | |
| Hydrochloric Acid SCHEMBL31234736 | 0.79 | HRH3 (0.57) | SIGMAR1HRH3ALDH1A1KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177562-B1 | Polymer, rubber composition and tire using the same | SUMITOMO RUBBER IND (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2184318-B1 | Rubber composition and tire | SUMITOMO RUBBER IND (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-8431644-B2 | Rubber composition and tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2013-04-30 | — | — | US | disclosed |
| EP-2182028-B1 | Rubber composition and tire | SUMITOMO RUBBER IND (JP) | 2012-12-12 | — | — | EP | disclosed |
| CN-101724127-A | Polymer, rubber composition and tire using the same | SUMITOMO RUBBER IND | 2010-06-09 | — | — | CN | disclosed |
| CN-101724184-A | Rubber composition and tire | SUMITOMO RUBBER IND | 2010-06-09 | — | — | CN | disclosed |
| CN-101724185-A | Rubber composition and tire | SUMITOMO RUBBER IND | 2010-06-09 | — | — | CN | disclosed |
| EP-2184318-A2 | Rubber composition and tire | Sumitomo Rubber Industries, Ltd. (JP) | 2010-05-12 | — | — | EP | disclosed |
| EP-2182028-A1 | Rubber composition and tire | Sumitomo Rubber Industries, Ltd. (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20100105826-A1 | RUBBER COMPOSITION AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100099810-A1 | POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100099795-A1 | RUBBER COMPOSITION AND TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2177562-A2 | Polymer, rubber composition and tire using the same | Sumitomo Rubber Industries, Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |