Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359431 | 1.00 | TSHR (0.47) | TSHRSMN1; SMN2PHGDHENPP2POLB | |
| SCHEMBL3359240 | 0.86 | ENPP2 (0.42) | ENPP2LMNAMEN1KMT2ACA2 | |
| SCHEMBL5182269 | 0.82 | MEN1 (0.50) | TSHRPOLBLMNAMEN1KMT2A | |
| Hydroquinone SCHEMBL1286582 | 0.77 | MEN1 (0.60) | SMN1; SMN2POLBLMNAMEN1KMT2A | |
| SCHEMBL30029777 | 0.76 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL21993467 | 0.76 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL15849846 | 0.76 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL34718 | 0.76 | TSHR (0.71) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL7847821 | 0.76 | NR1H4 (0.51) | SMN1; SMN2POLBMEN1KMT2ANTSR1 | |
| SCHEMBL3361558 | 0.76 | ALOX5 (0.50) | POLBLMNAMEN1KMT2ANTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081031-A1 | POLYMER ELECTROLYTE MEMBRANE FOR DIRECT METHANOL FUEL CELL AND DIRECT METHANOL FUEL CELL | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-04-01 | — | — | US | disclosed |