Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358276 | 0.86 | TSHR (0.47) | ENPP2LMNAMEN1KMT2ACA1 | |
| SCHEMBL3359431 | 0.86 | TSHR (0.47) | ENPP2LMNAMEN1KMT2ACA1 | |
| SCHEMBL3361558 | 0.78 | ALOX5 (0.50) | LMNABCL2L1BADMEN1NPC1 | |
| SCHEMBL28711090 | 0.78 | MEN1 (0.41) | ENPP2LMNAPTGS2MEN1NPC1 | |
| SCHEMBL2752103 | 0.77 | LMNA (0.52) | LMNAPTGS2BCL2L1BADMEN1 | |
| SCHEMBL66196 | 0.75 | LMNA (0.59) | LMNAMEN1KMT2ACA1CA2 | |
| SCHEMBL15106541 | 0.74 | HTR2A (0.39) | ENPP2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6914794 | 0.73 | LMNA (0.56) | LMNAMEN1KMT2ACA1CA2 | |
| SCHEMBL6914537 | 0.73 | LMNA (0.56) | LMNAMEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL3278762 | 0.73 | LMNA (0.56) | LMNAMEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081031-A1 | POLYMER ELECTROLYTE MEMBRANE FOR DIRECT METHANOL FUEL CELL AND DIRECT METHANOL FUEL CELL | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-04-01 | — | — | US | disclosed |