Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978373 | 0.86 | ALDH1A1 (0.67) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL15978372 | 0.86 | ALDH1A1 (0.67) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL15980320 | 0.84 | ALDH1A1 (0.65) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL15980984 | 0.84 | ALDH1A1 (0.65) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL15968251 | 0.84 | ALDH1A1 (0.65) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL15980319 | 0.84 | ALDH1A1 (0.65) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL15980975 | 0.84 | ALDH1A1 (0.65) | ALOX15ALDH1A1TRPV1FNTAFNTB | |
| SCHEMBL6913629 | 0.82 | ALDH1A1 (0.48) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL883432 | 0.80 | HDAC6 (0.41) | ALDH1A1HDAC6 | |
| SCHEMBL12743336 | 0.80 | HDAC6 (0.41) | ALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783111-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-04-08 | — | — | EP | disclosed |
| EP-2781522-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST | Sumitomo Chemical Company, Limited (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-7709651-B2 | asymmetriccomplex of copper(I) trifluoromethanesulfonate and 1,1-bis[2-[(4S)-(tert-butyl)-oxazoline]]cyclopropane is added to 3-methyl-2-butenyl acetate and ethyl diazoacetate using dichloroethane solvent to effect reaction to produce ethyl 3,3-dimethyl-2-(acetoxymethyl)cyclopropanecarboxylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-04 | — | — | US | disclosed |
| US-7705165-B2 | Method for producing optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-27 | — | — | US | disclosed |
| US-7671210-B2 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1783130-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-12-30 | — | — | EP | disclosed |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-01-31 | — | — | US | disclosed |
| EP-1783111-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1783130-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| US-20070032659-A1 | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1674445-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | ACSL6, AOC1, CA6 | ALOX15 593/4885ALDH1A1 1222/4885MMP1 4850/4885 |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | CBR3, C9, CBR1 | ALOX15 1218/4885ALDH1A1 1594/4885MMP1 4685/4885 |
| US-20070032659-A1 | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | CBR3, AOC3, CBR1 | ALOX15 956/4885ALDH1A1 185/4885MMP1 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.