Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477424 | 0.81 | RAB9A (0.33) | KDM4EALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL3358641 | 0.81 | RAB9A (0.33) | KDM4EALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL22658875 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL2825669 | 0.72 | TSHR (0.44) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL1968562 | 0.71 | MAPK1 (0.52) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL15440492 | 0.71 | MAPK1 (0.51) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL27825998 | 0.71 | KDM4E (0.47) | KDM4ERAB9ANPC1L3MBTL1PKM | |
| SCHEMBL2832760 | 0.70 | TSHR (0.43) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL18467314 | 0.70 | TSHR (0.43) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL16371512 | 0.69 | TSHR (0.46) | KDM4EALDH1A1CYP1A2KMT2AILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373648-B1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YL ACETIC ACIDS, METHOD FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| EP-2194052-A1 | Substituted 1.(1-thiazolyl)- and 1-(isothiazolyl)pyrazol-4-yl acetic acids, method for their production and their use as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2010-06-09 | — | — | EP | disclosed |