Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477424 | 1.00 | RAB9A (0.33) | RAB9ANPC1SMN1; SMN2KAT8TLR8 | |
| SCHEMBL3358643 | 0.81 | KDM4E (0.40) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL2474416 | 0.77 | GABRP (0.36) | RAB9ANPC1SMN1; SMN2TLR8TLR7 | |
| SCHEMBL6502840 | 0.74 | HCAR2 (0.39) | RAB9ANPC1SMN1; SMN2HCAR2GAA | |
| SCHEMBL14773411 | 0.74 | ALDH1A1 (0.37) | RAB9ANPC1SMN1; SMN2HCAR2GAA | |
| SCHEMBL22774382 | 0.74 | L3MBTL1 (0.40) | RAB9ANPC1HCAR2GAAMAPK1 | |
| SCHEMBL7938433 | 0.73 | NPC1 (0.34) | RAB9ANPC1SMN1; SMN2HCAR2GAA | |
| SCHEMBL5555727 | 0.72 | ALDH1A1 (0.33) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL2826243 | 0.70 | GRM5 (0.48) | RAB9ANPC1GAAKMT2AALDH1A1 | |
| SCHEMBL11162603 | 0.70 | ADRA2A (0.33) | RAB9ANPC1SMN1; SMN2HCAR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373648-B1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YL ACETIC ACIDS, METHOD FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| EP-2194052-A1 | Substituted 1.(1-thiazolyl)- and 1-(isothiazolyl)pyrazol-4-yl acetic acids, method for their production and their use as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2010-06-09 | — | — | EP | disclosed |