Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 10/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | DDO | Q99489 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389330 | 0.76 | KDM4E (0.43) | FASNCA1CA2MCL1UPP1 | |
| SCHEMBL3395242 | 0.76 | FASN (0.42) | FASNMCL1UPP1KDM4EALDH1A1 | |
| SCHEMBL3420696 | 0.74 | DAO (0.51) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL29732438 | 0.72 | DYRK1A (0.47) | CA1CA2MCL1DYRK1A | |
| SCHEMBL20115833 | 0.72 | DYRK1A (0.47) | CA1CA2MCL1DYRK1A | |
| SCHEMBL3432547 | 0.70 | GRIN2D (0.41) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL31628356 | 0.70 | FEN1 (0.40) | CA1CA2DYRK1A | |
| SCHEMBL17942038 | 0.68 | KDM4E (0.69) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL18152257 | 0.68 | DAO (0.53) | CA1CA2MCL1KDM4EALDH1A1 | |
| SCHEMBL12765007 | 0.68 | CA1 (0.37) | FASNCA1CA2MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |