Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | DDO | Q99489 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420415 | 0.78 | PGR (0.39) | DAOALDH1A1LMNADDOPGR | |
| SCHEMBL9390027 | 0.75 | DAO (0.68) | DAOALDH1A1LMNADDOGABRA1 | |
| SCHEMBL3422531 | 0.75 | DAO (0.51) | DAOALDH1A1DDOGABRA1GABRB2 | |
| SCHEMBL3358803 | 0.74 | FASN (0.40) | DAOALDH1A1DDOKDM4EMAPT | |
| SCHEMBL3420842 | 0.72 | DAO (0.38) | DAODDOGABRA1GABRB2GRIN2D | |
| SCHEMBL2914712 | 0.71 | ALDH1A1 (0.49) | DAOALDH1A1LMNADDOGABRA1 | |
| SCHEMBL3432547 | 0.71 | GRIN2D (0.41) | DAOALDH1A1DDOKDM4EMAPT | |
| SCHEMBL3425826 | 0.71 | DAO (0.37) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17942038 | 0.69 | KDM4E (0.69) | DAOALDH1A1LMNADDOKDM4E | |
| SCHEMBL15981323 | 0.69 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |