Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 8/20 | 0.42 |
| ▸ | DDO | Q99489 | 5/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 2/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387820 | 0.81 | UPP1 (0.39) | KDM4ETDP1DAODDOMCL1 | |
| SCHEMBL9389836 | 0.78 | UPP1 (0.42) | KDM4EDAODDOMCL1FASN | |
| SCHEMBL9389395 | 0.76 | KDM4E (0.46) | KDM4ETDP1DAODDOPLA2G7 | |
| SCHEMBL9389416 | 0.76 | DAO (0.66) | KDM4ETDP1DAODDOPLA2G7 | |
| SCHEMBL8583717 | 0.76 | DAO (0.66) | KDM4ETDP1DAODDOPLA2G7 | |
| SCHEMBL9388997 | 0.76 | DAO (0.66) | KDM4ETDP1DAODDOPLA2G7 | |
| SCHEMBL9393346 | 0.76 | DAO (0.49) | KDM4ETDP1DAODDOPLA2G7 | |
| SCHEMBL3358803 | 0.76 | FASN (0.40) | KDM4EDAODDOMCL1CA1 | |
| SCHEMBL9389922 | 0.76 | DAO (0.46) | DAODDOMCL1FASNUPP1 | |
| SCHEMBL9389937 | 0.76 | FASN (0.35) | DAODDOMCL1FASNUPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |