Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31584327 | 0.95 | DHODH (0.64) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL188820 | 0.95 | DHODH (0.64) | DHODHLMNAGAANAPRTMEN1 | |
| Hydrochloric Acid SCHEMBL23388066 | 0.93 | DHODH (0.62) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL288085 | 0.81 | DHODH (0.60) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL662027 | 0.80 | ALDH1A1 (0.61) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL1375514 | 0.80 | DHODH (0.64) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL29712338 | 0.80 | DHODH (0.64) | DHODHLMNAGAANAPRTMEN1 | |
| Hydrochloric Acid SCHEMBL7084810 | 0.79 | ALDH1A1 (0.59) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL9142184 | 0.79 | ALDH1A1 (0.59) | DHODHLMNAGAANAPRTMEN1 | |
| SCHEMBL9616246 | 0.78 | DHODH (0.66) | DHODHLMNAGAANAPRTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117360-A1 | METHOD FOR ANALYZING SUGAR CHAIN | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2023-04-20 | — | — | US | disclosed |
| US-10744211-B2 | Trifunctional and completely clearable specific targeting agents and methods thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2020-08-18 | — | — | US | disclosed |
| US-20180250425-A1 | TRIFUNCTIONAL AND COMPLETELY CLEARABLE SPECIFIC TARGETING AGENTS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2018-09-06 | — | — | US | disclosed |
| US-20140308205-A1 | TRIFUNCTIONAL AND COMPLETELY CLEARABLE SPECIFIC TARGETING AGENTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-10-16 | — | — | US | disclosed |
| WO-2010021639-A1 | ATTOMOLAR PROTEIN DETECTION IN COMPLEX DAMLE MATRICES WITH SEMI-HOMOGENEOUS FLUIDIC FORCE DISCRIMINATION ASSAYS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308205-A1 | TRIFUNCTIONAL AND COMPLETELY CLEARABLE SPECIFIC TARGETING AGENTS AND METHODS THEREOF | FCGR3B, FCGR2A, FCGR1A | DHODH 852/4885LMNA 4444/4885GAA 45/4885 |
| US-20180250425-A1 | TRIFUNCTIONAL AND COMPLETELY CLEARABLE SPECIFIC TARGETING AGENTS AND METHODS THEREOF | FCGR3B, FCGR2A, FCGR1A | DHODH 852/4885LMNA 4444/4885GAA 45/4885 |
| US-10744211-B2 | Trifunctional and completely clearable specific targeting agents and methods thereof | FCGR3B, FCGR2A, FCGR1A | DHODH 852/4885LMNA 4444/4885GAA 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.