SCHEMBL3359306

SCHEMBL3359306

COc1cc(C=Cc2ccc(N3CCN(C)CC3)cc2)cc(OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 4/20 0.57
CYP1A1 P04798 4/20 0.57
CYP1B1 Q16678 4/20 0.57
MAPT P10636 3/20 0.57
ESR1 P03372 3/20 0.57
ABL1 P00519 2/20 0.57
TTR P02766 2/20 0.57
ABCB1 P08183 2/20 0.57
ALOX5 P09917 2/20 0.57
BCR P11274 2/20 0.57
CYP19A1 P11511 2/20 0.57
PTGS2 P35354 2/20 0.57
CYP1A2 P05177 2/20 0.57
TUBB4A P04350 2/20 0.57
TUBB P07437 2/20 0.57
TUBA3C P0DPH7 2/20 0.57
AHR P35869 2/20 0.57
TUBA1B P68363 2/20 0.57
TUBA4A P68366 2/20 0.57
TUBB4B P68371 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3359432 1.00 NQO2 (0.57) NQO2CYP1A1CYP1B1MAPTESR1
SCHEMBL3363814 0.85 NQO2 (0.57) NQO2CYP1A1CYP1B1MAPTESR1
SCHEMBL3359954 0.85 NQO2 (0.57) NQO2CYP1A1CYP1B1MAPTESR1
SCHEMBL3431700 0.81 MAPT (0.60) NQO2CYP1A1CYP1B1MAPTESR1
SCHEMBL3431698 0.81 MAPT (0.60) NQO2CYP1A1CYP1B1MAPTESR1
Hydrochloric Acid SCHEMBL3432295 0.80 MAPT (0.58) NQO2CYP1A1CYP1B1MAPTESR1
Hydrochloric Acid SCHEMBL3432297 0.80 MAPT (0.58) NQO2CYP1A1CYP1B1MAPTESR1
SCHEMBL23657292 0.78 ADRB1 (0.58) MAPTKDM4EMEN1NPC1GAA
SCHEMBL424503 0.78 DRD2 (0.66) MAPTKDM4EMEN1NPC1GAA
SCHEMBL10769390 0.76 HTR3E (0.56) NQO2CYP1A1CYP1B1MAPTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO disclosed