Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.56 |
| ▸ | BMP4 | P12644 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.41 |
| ▸ | ABL2 | P42684 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362290 | 0.78 | GRM4 (0.55) | GRM4RAB9AKCNH2KDM4ENPC1 | |
| SCHEMBL6448933 | 0.74 | BCHE (0.46) | RAB9ACYP1A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL22349328 | 0.73 | KDM5A (0.59) | RAB9AKDM4EKDM5AKDM4CKDM5B | |
| SCHEMBL1227713 | 0.71 | CYP1A2 (0.60) | GRM4BMP4RAB9AHTR2BMTNR1A | |
| SCHEMBL27917128 | 0.71 | CYP1A2 (0.60) | GRM4BMP4RAB9AHTR2BMTNR1A | |
| SCHEMBL29699887 | 0.71 | CYP1A2 (0.60) | GRM4BMP4RAB9AHTR2BMTNR1A | |
| SCHEMBL6450478 | 0.71 | PDCD1 (0.49) | RAB9ACYP1A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL30487734 | 0.69 | CYP1A2 (0.58) | GRM4BMP4RAB9AHTR2BMTNR1A | |
| SCHEMBL6627903 | 0.69 | TGFBR1 (0.67) | GRM4BMP4RAB9ATGFBR1MAPK14 | |
| SCHEMBL7918743 | 0.68 | MAPT (0.56) | GRM4BMP4RAB9ATGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |