Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858961 | 0.76 | KMT2A (0.47) | TSHRALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11250944 | 0.72 | MAPKAPK2 (0.57) | MAPKAPK2MAPK1CYP2D6TSHRALDH1A1 | |
| Carbazole SCHEMBL8411559 | 0.71 | ALDH1A1 (0.74) | MAPK1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL1801427 | 0.71 | MAPKAPK2 (0.66) | MAPKAPK2MAPK1CYP2D6TSHRALDH1A1 | |
| SCHEMBL11374096 | 0.70 | SIRT1 (0.43) | MAPKAPK2MAPK1CYP2D6TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL19139018 | 0.70 | MAPKAPK2 (0.45) | MAPKAPK2MAPK1CYP2D6TSHRALDH1A1 | |
| SCHEMBL27048383 | 0.69 | PLAU (0.68) | MAPK1CYP2D6TSHRALDH1A1KDM4E | |
| Acridone SCHEMBL30381794 | 0.68 | GAA (0.78) | MAPK1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL1870145 | 0.68 | SIRT1 (0.76) | MAPKAPK2MAPK1CYP2D6TSHRALDH1A1 | |
| Carbazole SCHEMBL30528395 | 0.67 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069248-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-18 | — | — | US | claimed |
| WO-2010017921-A3 | HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| US-20100069248-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-18 | — | — | US | disclosed |
| US-20100069248-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-18 | — | — | US | disclosed |
| WO-2010017921-A2 | HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010017921-A2 | HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069248-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | DDT, CYP2D6, CYP2A6 | MAPKAPK2 1921/4885MAPK1 1950/4885CYP2D6 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.