Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valeric Acid SCHEMBL9879921 | 0.92 | AKR1B1 (0.56) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| Acetic Acid SCHEMBL343375 | 0.85 | MAPT (0.63) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| 3-Methylbutanoic Acid SCHEMBL3359773 | 0.82 | AKR1B1 (0.57) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29375440 | 0.82 | MAPT (0.67) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL86392 | 0.82 | MAPT (0.67) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| Ethyl Acetate SCHEMBL3359951 | 0.80 | ALDH1A1 (0.61) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9218019 | 0.77 | AKR1B1 (0.62) | AKR1B1MAPTALDH1A1RAB9A | |
| SCHEMBL11197534 | 0.76 | AKR1B1 (0.60) | AKR1B1MAPTALDH1A1RAB9A | |
| SCHEMBL9870088 | 0.76 | MAPT (0.54) | AKR1B1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL246421 | 0.76 | ALDH1A1 (0.74) | MAPTALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2666770-A1 | Process for obtaining olopatadine and intermediates | Crystal Pharma S.A.U (ES) | 2013-11-27 | — | — | EP | disclosed |
| EP-2145882-B1 | Process for obtaining olopatadine and intermediates | CRYSTAL PHARMA SAU (ES) | 2013-08-21 | — | — | EP | disclosed |
| EP-2145882-A1 | Process for obtaining olopatadine and intermediates | Ragactives, S.L.U. (ES) | 2010-01-20 | — | — | EP | disclosed |