Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL28638939 | 0.86 | MAOA (0.61) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| Acetic Acid SCHEMBL343375 | 0.84 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| Anthrone SCHEMBL27724215 | 0.83 | MAOA (0.58) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10824721 | 0.82 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL86392 | 0.81 | MAPT (0.67) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL29375440 | 0.81 | MAPT (0.67) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL11085181 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8141977 | 0.80 | AKR1B1 (0.56) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| Butyric Acid SCHEMBL3359947 | 0.80 | AKR1B1 (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| Anthrone SCHEMBL28349280 | 0.79 | MAOA (0.53) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2666770-A1 | Process for obtaining olopatadine and intermediates | Crystal Pharma S.A.U (ES) | 2013-11-27 | — | — | EP | disclosed |
| EP-2145882-B1 | Process for obtaining olopatadine and intermediates | CRYSTAL PHARMA SAU (ES) | 2013-08-21 | — | — | EP | disclosed |
| EP-2145882-A1 | Process for obtaining olopatadine and intermediates | Ragactives, S.L.U. (ES) | 2010-01-20 | — | — | EP | disclosed |