SCHEMBL3359956

SCHEMBL3359956

Cc1oc2c(C)c3oc(=O)cc(C)c3cc2c1CNCCCNCCCN

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
KDM4E B2RXH2 7/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
HTR2C P28335 1/20 0.40
ADORA2A P29274 1/20 0.40
L3MBTL1 Q9Y468 4/20 0.39
HSD17B10 Q99714 3/20 0.36
MAPT P10636 2/20 0.36
MCL1 Q07820 2/20 0.36
UBE2N P61088 1/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 4/20 0.35
HPGD P15428 3/20 0.35
HTT P42858 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FHIT P49789 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3362820 0.99 MAOB (0.40) MAOBMAOAKDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4182826 0.98 MAOB (0.39) MAOBMAOAKDM4EALDH1A1MAPK1
SCHEMBL3360474 0.98 MAOA (0.42) MAOBMAOAKDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4192607 0.97 MAOA (0.41) MAOBMAOAKDM4EALDH1A1MAPK1
SCHEMBL3359444 0.94 MAOA (0.41) MAOBMAOAKDM4EALDH1A1MAPK1
SCHEMBL8903963 0.93 MAOA (0.41) MAOBMAOAKDM4EALDH1A1MAPK1
SCHEMBL3360003 0.93 MAOA (0.41) MAOBMAOAKDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4193524 0.93 MAOA (0.41) MAOBMAOAKDM4EALDH1A1MAPK1
SCHEMBL3359425 0.93 MAOA (0.44) MAOBMAOAKDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4188117 0.92 MAOA (0.40) MAOBMAOAKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1508345-B1 System and method for the reduction of small organic compounds from blood products CERUS CORP (US) 2013-09-25 EP claimed
US-7611831-B2 Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix CERUS CORPORATION (US) 2009-11-03 US claimed
EP-1776952-A2 Photodecontamination of pathogens in blood Cerus Corporation (US) 2007-04-25 EP claimed
EP-0707476-B1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD CERUS CORP (US) 2007-02-14 EP claimed
US-20060093999-A1 For reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological activity; comprises highly porous adsorbent particles CERUS CORPORATION 2006-05-04 US claimed
US-7037642-B2 Removing compounds from blood products with porous particles immobilized in a matrix CERUS CORPORATION (US) 2006-05-02 US claimed
US-6951713-B2 Absorbing pathogen-inactivating compounds with porous particles immobilized in a matrix CERUS CORPORATION (US) 2005-10-04 US claimed
US-20050142542-A1 ABSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX CERUS CORPORATION 2005-06-30 US claimed
EP-1508345-A1 Absorbents and devices for the reduction of small organic compounds from blood products Cerus Corporation (US) 2005-02-23 EP claimed
EP-0954374-B1 ADSORBENS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS CERUS CORP (US) 2004-11-24 EP claimed
US-5593823-A FOR A SUFFICIENT DURATION, INTENSITY AND WAVELENGTH CERUS CORPORATION (US) 1997-01-14 US claimed
US-20180185484-A1 PREPARATION AND USE OF PLATELET PRODUCTS MIDCAP FINANCIAL TRUST 2018-07-05 US disclosed
EP-3247351-A1 PREPARATION AND USE OF PLATELET PRODUCTS Cerus Corporation (US) 2017-11-29 EP disclosed
US-20160354533-A1 ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX CERUS CORPORATION (US) 2016-12-08 US disclosed
WO-2016115535-A1 PREPARATION AND USE OF PLATELET PRODUCTS CERUS CORPORATION (US) 2016-07-21 WO disclosed
WO-1997021346-A1 INACTIVATION OF NON-ENVELOPED VIRUS CERUS CORPORATION (US) 1997-06-19 WO disclosed
WO-1996039820-A1 METHODS OF INACTIVATING LEUKOCYTES AND INHIBITING CYTOKINE PRODUCTION IN BLOOD PRODUCTS CERUS CORPORATION (US) 1996-12-19 WO disclosed
WO-1996014739-A1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD CERUS CORPORATION (US) 1996-05-23 WO disclosed
EP-0707476-A1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD STERITECH, INC (US) 1996-04-24 EP disclosed
WO-1995000141-A1 COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD STERITECH, INC. (US) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180185484-A1 PREPARATION AND USE OF PLATELET PRODUCTS PLTP, MPL, PFKP MAOB 3017/4885MAOA 3650/4885KDM4E 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.