SCHEMBL3360067

SCHEMBL3360067

C=Cc1ccc(CCN(C)CCc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.56
TAAR1 Q96RJ0 1/20 0.52
AOC3 Q16853 1/20 0.48
FDPS P14324 1/20 0.45
KCNH2 Q12809 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360495 0.92 SIGMAR1 (0.54) SIGMAR1TAAR1AOC3ALDH1A1TSHR
SCHEMBL3356681 0.86 SIGMAR1 (0.45) SIGMAR1TAAR1KCNH2ALDH1A1
SCHEMBL11442805 0.84 CARM1 (0.41) SIGMAR1TAAR1AOC3KCNH2ALDH1A1
SCHEMBL3358825 0.84 ALDH1A1 (0.41) SIGMAR1TAAR1KCNH2ALDH1A1
SCHEMBL3359358 0.83 SIGMAR1 (0.45) SIGMAR1KCNH2ALDH1A1
SCHEMBL3357171 0.83 TAAR1 (0.44) SIGMAR1TAAR1AOC3KCNH2ALDH1A1
SCHEMBL9806380 0.82 ALDH1A1 (0.59) TAAR1KCNH2ALDH1A1TSHR
Demelverine SCHEMBL1516521 0.82 SIGMAR1 (0.76) SIGMAR1TAAR1AOC3FDPSSLC6A2
SCHEMBL17409806 0.81 BCHE (0.49) SIGMAR1AOC3ALDH1A1TSHR
SCHEMBL27802873 0.81 TAAR1 (0.43) SIGMAR1TAAR1AOC3KCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2177562-B1 Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
EP-2184318-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2014-03-19 EP disclosed
CN-101724185-B Rubber composition and tire SUMITOMO RUBBER IND 2013-10-23 CN disclosed
CN-101724184-B Rubber composition and tire SUMITOMO RUBBER IND 2013-05-01 CN disclosed
US-8431644-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-04-30 US disclosed
EP-2182028-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-12-12 EP disclosed
CN-101724185-A Rubber composition and tire SUMITOMO RUBBER IND 2010-06-09 CN disclosed
CN-101724184-A Rubber composition and tire SUMITOMO RUBBER IND 2010-06-09 CN disclosed
CN-101724127-A Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND 2010-06-09 CN disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed