Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL7172489 | 0.91 | LMNA (0.55) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL28023071 | 0.87 | TSHR (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL30619866 | 0.83 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL30533037 | 0.83 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL3636689 | 0.81 | GPR84 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL27528105 | 0.78 | MAPT (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| Pimelic Acid SCHEMBL28190686 | 0.78 | MAPT (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL7054977 | 0.77 | TSHR (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL7053358 | 0.77 | TSHR (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| Propene SCHEMBL7054981 | 0.77 | TSHR (0.67) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8821859-B2 | Methods and articles for the delivery of therapeutic agents | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-09-02 | — | — | US | claimed |
| US-9220773-B2 | Pharmaceutical composition | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2015-12-29 | — | — | US | disclosed |
| US-20140004185-A1 | PHARMACEUTICAL COMPOSITION | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2014-01-02 | — | — | US | disclosed |
| EP-2642979-A1 | A PHARMACEUTICAL COMPOSITION | University Of The Witwatersrand, Johannesburg (ZA) | 2013-10-02 | — | — | EP | disclosed |
| US-8425900-B2 | Method of delivering a protein into a cell | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-04-23 | — | — | US | disclosed |
| WO-2012070029-A1 | A PHARMACEUTICAL COMPOSITION | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2012-05-31 | — | — | WO | disclosed |
| US-20100119501-A1 | METHOD OF DELIVERING A PROTEIN INTO A CELL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-05-13 | — | — | US | disclosed |
| EP-2152241-A1 | METHOD OF DELIVERING A PROTEIN INTO A CELL | Agency for Science, Technology And Research (SG) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008133597-A1 | METHOD OF DELIVERING A PROTEIN INTO A CELL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119501-A1 | METHOD OF DELIVERING A PROTEIN INTO A CELL | LNPEP, ANXA6, PPHLN1 | GPR84 3521/4885PPARG 3969/4885PPARD 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.