Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361800 | 0.90 | CTSL (0.43) | DPP4MEN1KMT2ARXFP1CTSL | |
| SCHEMBL3362196 | 0.83 | DPP4 (0.46) | DPP4PDE10A | |
| SCHEMBL3361000 | 0.83 | DPP4 (0.61) | DPP4MEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL3362959 | 0.82 | DPP4 (0.40) | DPP4CTSSPDE10A | |
| Hydrochloric Acid SCHEMBL3362995 | 0.82 | DPP4 (0.61) | DPP4MEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL3363192 | 0.82 | CYP3A4 (0.41) | DPP4MEN1KMT2APDE10AALDH1A1 | |
| SCHEMBL3361880 | 0.81 | DPP4 (0.47) | DPP4PDE10A | |
| SCHEMBL3361175 | 0.79 | HPGD (0.44) | DPP4MEN1KMT2ARXFP1CTSL | |
| SCHEMBL3365064 | 0.78 | KDM4E (0.43) | DPP4MEN1KMT2APDE10AALDH1A1 | |
| SCHEMBL3361886 | 0.78 | DPP4 (0.41) | DPP4MEN1KMT2ARXFP1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |