Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361800 | 0.92 | CTSL (0.43) | L3MBTL1DPP4MAPK1MAPTMEN1 | |
| SCHEMBL3363215 | 0.83 | DPP4 (0.56) | RECQLALDH1A1RIPK1HPGDDPP4 | |
| Hydrochloric Acid SCHEMBL3361965 | 0.83 | DPP4 (0.57) | RECQLALDH1A1RIPK1HPGDDPP4 | |
| SCHEMBL3360434 | 0.82 | DPP4 (0.41) | ALDH1A1DPP4PDE10AMEN1KMT2A | |
| SCHEMBL3365064 | 0.81 | KDM4E (0.43) | ALDH1A1NPSR1DPP4KDM4EPDE10A | |
| SCHEMBL3363185 | 0.79 | NAMPT (0.39) | CYP3A4RECQLALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL3362959 | 0.79 | DPP4 (0.40) | DPP4PDE10A | |
| SCHEMBL3361880 | 0.78 | DPP4 (0.47) | DPP4PDE10A | |
| SCHEMBL3362196 | 0.78 | DPP4 (0.46) | DPP4PDE10A | |
| SCHEMBL3361175 | 0.78 | HPGD (0.44) | HPGDDPP4MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |