Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361800 | 0.84 | CTSL (0.43) | KMT2AMEN1DPP4LTB4RLTB4R2 | |
| SCHEMBL3363381 | 0.84 | DPP4 (0.55) | KDM4EALDH1A1TDP1AVPR1BHIF1A | |
| Hydrochloric Acid SCHEMBL3369641 | 0.83 | DPP4 (0.56) | KDM4EALDH1A1TDP1AVPR1BHIF1A | |
| SCHEMBL3363192 | 0.81 | CYP3A4 (0.41) | KDM4EALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3362959 | 0.80 | DPP4 (0.40) | DPP4PDE10A | |
| SCHEMBL3360434 | 0.78 | DPP4 (0.41) | ALDH1A1KMT2AMEN1DPP4PDE10A | |
| SCHEMBL3361880 | 0.78 | DPP4 (0.47) | DPP4PDE10A | |
| SCHEMBL3362196 | 0.78 | DPP4 (0.46) | DPP4PDE10A | |
| SCHEMBL3363213 | 0.77 | TLR8 (0.40) | KDM4EALDH1A1TDP1HIF1AKMT2A | |
| SCHEMBL3362189 | 0.74 | DPP4 (0.43) | KDM4ECYP1A2DPP4ATMPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |