Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812020 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP1A2 | |
| SCHEMBL11498930 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CYP1A2SMN1; SMN2 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL53540 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2489450 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL4886939 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TDP1SMN1; SMN2 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL20819425 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL21574302 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP1A2 | |
| SCHEMBL22039124 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL10926107 | 0.72 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2 | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL8953543 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343964-B2 | Indolic derivatives, their preparation processes and their uses in particular as antibacterials | UNIVERSITE JOSEPH FOURIER (FR) | 2013-01-01 | — | — | US | disclosed |
| US-20100144726-A1 | NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS | UNIVERSITE JOSEPH FOURIER (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144726-A1 | NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS | GPBAR1, TPH1, GPER1 | ALDH1A1 2563/4885HSD17B10 2368/4885TDP1 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.