SCHEMBL2489450

SCHEMBL2489450

C=CCN(CC=C)C(=C)COCC(=C)N(CC=C)CC=C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16500488 0.80 ALDH1A1 (0.46) ALDH1A1
SCHEMBL9259862 0.78 ALDH1A1 (0.42) ALDH1A1
SCHEMBL3360577 0.74 ALDH1A1 (0.41) ALDH1A1
SCHEMBL2641242 0.73 ALDH1A1 (0.58) ALDH1A1
SCHEMBL11812020 0.72 ALDH1A1 (0.39) ALDH1A1
SCHEMBL6685776 0.69 ALDH1A1 (0.41) ALDH1A1
SCHEMBL21574302 0.68 ALDH1A1 (0.41) ALDH1A1
SCHEMBL22039124 0.68 ALDH1A1 (0.41) ALDH1A1
SCHEMBL822281 0.67 ALDH1A1 (0.44) ALDH1A1
SCHEMBL24178952 0.66 ALDH1A1 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476785-B1 Processes for the preparation of aminoethers OSI SPECIALTIES INC (US) 1995-12-06 EP claimed
US-5214142-A PROCESSES FOR THE PREPARATION OF AMINOETHERS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-05-25 US claimed
EP-0476785-A1 Processes for the preparation of aminoethers OSi Specialties, Inc. (US) 1992-03-25 EP claimed
EP-0103453-B1 ONE-PART MOISTURE-CURABLE POLYURETHANE ADHESIVE, COATING, AND SEALANT COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-07-27 EP claimed
US-4511626-A BIS/2-/DIALKYLAMINO/ALKYL/ETHER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-16 US claimed
EP-0103453-A2 One-part moisture-curable polyurethane adhesive, coating, and sealant compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-03-21 EP claimed
JP-4270252-A None JP disclosed
EP-2371831-B1 PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND NIPPON SODA CO (JP) 2016-09-07 EP disclosed
US-9133098-B2 Process for producing organolithium compound and process for producing substituted aromatic compound NIPPON SODA CO., LTD. (JP) 2015-09-15 US disclosed
US-20150025276-A1 PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND NIPPON SODA CO., LTD. (JP) 2015-01-22 US disclosed
US-8871970-B2 Process for producing organolithium compound and process for producing substituted aromatic compound NIPPON SODA CO., LTD. (JP) 2014-10-28 US disclosed
CN-102459396-A Carbon nanotubes comprising hydroxyl groups, method for producing same and polyurethane polymer comprising said carbon nanotubes BAYER MATERIALSCIENCE AG 2012-05-16 CN disclosed
CN-102395667-A Fabric care compositions comprising organosiloxane polymers PROCTER & GAMBLE 2012-03-28 CN disclosed
EP-0392170-A2 Thermosetting polyurethane adhesive compositions and processes for producing the same RHEOX INTERNATIONAL, INC. (US) 1990-10-17 EP disclosed
EP-0392171-A2 Foamable thermosetting polyurethane structural adhesive compositions and processes for producing the same RHEOX INTERNATIONAL, INC. (US) 1990-10-17 EP disclosed
EP-0194742-B1 MOISTURE-CURABLE POLYURETHANE COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-02 EP disclosed
US-4839455-A TRIISOCYANATE PREPOLYMKKER ANDD EPOXY SILNAE CROSSLINKER; WOOD COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-06-13 US disclosed
EP-0194742-A1 Moisture-curable polyurethane composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-17 EP disclosed
US-4539345-A ADHESIVES, COATINGS SEALANTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-09-03 US disclosed
US-4511626-A BIS/2-/DIALKYLAMINO/ALKYL/ETHER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025276-A1 PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND C9, TRPA1, PKD1 ALDH1A1 4118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.