SCHEMBL3360658

SCHEMBL3360658

O=C(O)c1ccc(Oc2cccc3c(Oc4ccc(C(=O)O)c(C(=O)O)c4)cccc23)cc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
HPSE Q9Y251 1/20 0.55
KDM4E B2RXH2 1/20 0.54
PYGL P06737 11/20 0.52
PYGM P11217 11/20 0.52
MEN1 O00255 1/20 0.51
MITF O75030 1/20 0.51
LMNA P02545 1/20 0.51
KMT2A Q03164 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 1/20 0.50
GALK1 P51570 1/20 0.49
CASP6 P55212 1/20 0.49
MCL1 Q07820 1/20 0.49
PLEC Q15149 1/20 0.49
TDP1 Q9NUW8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27928487 0.91 POLB (0.64) POLBHPSEKDM4EPYGLPYGM
SCHEMBL29664286 0.87 POLB (0.65) POLBHPSEKDM4EPYGLPYGM
SCHEMBL7969637 0.87 POLB (0.65) POLBHPSEKDM4EPYGLPYGM
SCHEMBL4555111 0.86 HPSE (0.44) POLBHPSEKDM4EPYGLPYGM
SCHEMBL28650646 0.86 POLB (0.63) POLBHPSEKDM4EPYGLPYGM
SCHEMBL31152670 0.85 POLB (0.56) POLBHPSEKDM4EPYGLPYGM
SCHEMBL27946716 0.85 POLB (0.54) POLBHPSEKDM4EPYGLPYGM
SCHEMBL6891584 0.84 POLB (0.66) POLBHPSEKDM4EPYGLPYGM
SCHEMBL28634306 0.84 POLB (0.61) POLBHPSEKDM4EPYGLPYGM
SCHEMBL716921 0.83 PYGL (0.53) POLBHPSEKDM4EPYGLPYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009506349-A 2009-02-12 JP claimed
EP-1904603-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS Akron Polymer Systems (US) 2008-04-02 EP claimed
WO-2007011911-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2007-01-25 WO claimed
US-20070014938-A1 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS, INC. 2007-01-18 US claimed
US-20100132975-A1 INSULATED ELECTRICAL WIRE, ELECTRICAL COIL, AND MOTOR SUMITOMO ELECTRIC WINTEC, INC. (JP) 2010-06-03 US disclosed
US-7438957-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKON POLYMER SYSTEMS (US) 2008-10-21 US disclosed
EP-1904603-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS Akron Polymer Systems (US) 2008-04-02 EP disclosed
WO-2007011911-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2007-01-25 WO disclosed
US-20070014938-A1 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS, INC. 2007-01-18 US disclosed