SCHEMBL27928487

SCHEMBL27928487

O=C(O)c1ccc(Oc2cccc3ccccc23)cc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.64
MEN1 O00255 1/20 0.64
MITF O75030 1/20 0.64
LMNA P02545 1/20 0.64
KMT2A Q03164 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
PYGM P11217 8/20 0.56
PYGL P06737 7/20 0.56
MCL1 Q07820 2/20 0.53
BCL2L1 Q07817 1/20 0.53
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
HPSE Q9Y251 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.49
SIRT1 Q96EB6 1/20 0.49
SIRT3 Q9NTG7 1/20 0.49
KDM4E B2RXH2 1/20 0.49
CDC25B P30305 1/20 0.49
GALK1 P51570 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360658 0.91 POLB (0.55) POLBMEN1MITFLMNAKMT2A
SCHEMBL7257247 0.87 WDR5 (0.58) POLBMEN1MITFLMNAKMT2A
SCHEMBL7956405 0.85 PYGM (0.68) POLBMEN1KMT2AL3MBTL1PYGM
SCHEMBL29664286 0.85 POLB (0.65) POLBPYGMPYGLMCL1HPSE
SCHEMBL7969637 0.85 POLB (0.65) POLBPYGMPYGLMCL1HPSE
SCHEMBL8646572 0.84 PYGM (0.53) POLBMEN1MITFLMNAKMT2A
SCHEMBL28553992 0.84 PYGL (0.53) POLBMEN1MITFLMNAKMT2A
SCHEMBL28650646 0.84 POLB (0.63) POLBPYGMPYGLMCL1HPSE
SCHEMBL7261933 0.83 WDR5 (0.50) POLBMEN1MITFLMNAKMT2A
SCHEMBL7126593 0.82 PYGL (0.71) POLBMEN1MITFLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103183961-B Solution of polyamic acid resin containing interpenetrating network polymer and polyimide metal laminate IND TECH RES INST 2015-03-04 CN disclosed
CN-103183961-A Solution of polyamic acid resin containing interpenetrating network polymer and polyimide metal laminate IND TECH RES INST 2013-07-03 CN disclosed