Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576614 | 0.83 | ALOX15 (0.48) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL3358282 | 0.78 | ALOX15 (0.44) | ALOX15HIF1AEPAS1CYP3A4ALDH1A1 | |
| SCHEMBL10651515 | 0.78 | ALOX15 (0.44) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL3358285 | 0.76 | ALOX15 (0.47) | ALOX15HIF1AEPAS1CYP3A4ALDH1A1 | |
| SCHEMBL23987115 | 0.76 | ALOX15 (0.56) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL583687 | 0.74 | ALOX15 (0.60) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL14330210 | 0.73 | ALOX15 (0.48) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL988359 | 0.73 | ALOX15 (0.59) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL8254858 | 0.72 | ALOX15 (0.52) | ALOX15KMT2AHIF1AEPAS1CYP3A4 | |
| SCHEMBL11802270 | 0.72 | ALOX15 (0.52) | ALOX15KMT2AHIF1AEPAS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781522-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST | Sumitomo Chemical Company, Limited (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-7705165-B2 | Method for producing optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | ACSL6, AOC1, CA6 | ALOX15 593/4885KMT2A 4040/4885HIF1A 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.