Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 2/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364123 | 0.85 | KDM4E (0.48) | KMT2AMEN1HPGDL3MBTL1HSD17B10 | |
| SCHEMBL3365213 | 0.84 | DPP4 (0.47) | DPP4 | |
| SCHEMBL3361923 | 0.81 | DPP4 (0.64) | DPP4TP53 | |
| SCHEMBL3361983 | 0.80 | DPP4 (0.56) | DPP4 | |
| SCHEMBL7720666 | 0.80 | DPP4 (0.61) | KMT2AMEN1DPP4HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3362783 | 0.79 | DPP4 (0.62) | KMT2AMEN1DPP4HPGDL3MBTL1 | |
| SCHEMBL3363973 | 0.79 | DPP4 (0.43) | DPP4 | |
| SCHEMBL3361990 | 0.78 | DPP4 (0.44) | DPP4 | |
| SCHEMBL3365143 | 0.77 | PDE10A (0.51) | KMT2AMEN1DPP4TP53HPGD | |
| SCHEMBL3361880 | 0.76 | DPP4 (0.47) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |