Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | TEK | Q02763 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365213 | 0.86 | DPP4 (0.47) | DPP4 | |
| SCHEMBL3362189 | 0.86 | DPP4 (0.43) | DPP4KDM4EMAPK1PDE10ACYP1A2 | |
| SCHEMBL3361298 | 0.85 | DPP4 (0.46) | DPP4KDM4EMAPK1AURKAMET | |
| SCHEMBL3365143 | 0.84 | PDE10A (0.51) | DPP4KDM4EPDE10ACYP1A2PKM | |
| SCHEMBL3361923 | 0.82 | DPP4 (0.64) | DPP4 | |
| SCHEMBL3363973 | 0.80 | DPP4 (0.43) | DPP4 | |
| SCHEMBL3361990 | 0.80 | DPP4 (0.44) | DPP4KDM4E | |
| SCHEMBL3360972 | 0.80 | KMT2A (0.44) | DPP4 | |
| SCHEMBL3361880 | 0.78 | DPP4 (0.47) | DPP4PDE10A | |
| SCHEMBL3361175 | 0.76 | HPGD (0.44) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |