Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361307 | 0.86 | DPP4 (0.46) | DPP4CTSLALDH1A1PDPK1 | |
| SCHEMBL3362196 | 0.84 | DPP4 (0.46) | DPP4 | |
| SCHEMBL3365213 | 0.84 | DPP4 (0.47) | DPP4CTSLPRMT5WDR77ENPP1 | |
| SCHEMBL3361923 | 0.82 | DPP4 (0.64) | DPP4 | |
| SCHEMBL3361175 | 0.80 | HPGD (0.44) | DPP4CTSL | |
| SCHEMBL3361983 | 0.80 | DPP4 (0.56) | DPP4KDM4E | |
| SCHEMBL3363973 | 0.79 | DPP4 (0.43) | DPP4CTSLPRMT5WDR77 | |
| SCHEMBL3360972 | 0.78 | KMT2A (0.44) | DPP4 | |
| SCHEMBL3365143 | 0.77 | PDE10A (0.51) | DPP4KDM4EALDH1A1 | |
| SCHEMBL3361880 | 0.76 | DPP4 (0.47) | DPP4PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |