Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365213 | 0.85 | DPP4 (0.47) | DPP4PRMT5WDR77CTSL | |
| SCHEMBL3362437 | 0.83 | DPP4 (0.45) | DPP4MAPKAPK2CTSL | |
| SCHEMBL3361880 | 0.83 | DPP4 (0.47) | DPP4PRMT5WDR77 | |
| SCHEMBL3361992 | 0.82 | DPP4 (0.50) | DPP4MAPKAPK2 | |
| SCHEMBL3361995 | 0.82 | DPP4 (0.39) | DPP4PRMT5WDR77ATM | |
| SCHEMBL3361923 | 0.81 | DPP4 (0.64) | DPP4 | |
| SCHEMBL3361983 | 0.80 | DPP4 (0.56) | DPP4 | |
| SCHEMBL3360972 | 0.79 | KMT2A (0.44) | DPP4 | |
| SCHEMBL3361990 | 0.79 | DPP4 (0.44) | DPP4PRMT5WDR77CTSL | |
| SCHEMBL3362189 | 0.79 | DPP4 (0.43) | DPP4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |