SCHEMBL336107

SCHEMBL336107

O=C(O)c1cccc(C(=O)O)c1F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
ALB P02768 1/20 0.60
ALOX15 P16050 1/20 0.60
CES2 O00748 1/20 0.52
BCHE P06276 1/20 0.52
CES1 P23141 1/20 0.52
NAPRT Q6XQN6 2/20 0.52
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
TSHR P16473 1/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
ASPH Q12797 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18866791 0.89 ALB (0.50) ALDH1A1ALBALOX15CES2BCHE
SCHEMBL365453 0.87 CES2 (0.71) ALDH1A1ALBALOX15CES2BCHE
SCHEMBL19923221 0.87 HSD17B10 (0.59) ALDH1A1ALBALOX15CES2BCHE
SCHEMBL27805264 0.85 CES2 (0.68) ALDH1A1ALBALOX15CES2BCHE
SCHEMBL5231025 0.85 ALDH1A1 (0.60) ALDH1A1ALBALOX15CES2BCHE
SCHEMBL28157809 0.85 CES2 (0.68) ALDH1A1ALBALOX15CES2BCHE
SCHEMBL27786089 0.85 CES2 (0.68) ALDH1A1ALBALOX15CES2BCHE
Hydrochloric Acid SCHEMBL3199889 0.85 CES2 (0.68) ALDH1A1ALBALOX15CES2BCHE
Hydrochloric Acid SCHEMBL31609616 0.85 CES2 (0.68) ALDH1A1ALBALOX15CES2BCHE
Fluoride SCHEMBL6441128 0.85 CES2 (0.68) ALDH1A1ALBALOX15CES2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN claimed
EP-2452931-B1 METHOD FOR PREPARING TRICYCLIC DERIVATIVES JE IL PHARMACEUTICAL CO LTD (KR) 2017-05-17 EP claimed
US-8742160-B2 Method for preparing tricyclic derivatives JE IL PHARMACEUTICAL CO., LTD. (KR) 2014-06-03 US claimed
EP-2452931-A2 METHOD FOR PREPARING TRICYCLIC DERIVATIVES Jeil Pharmaceutical Co., Ltd. (KR) 2012-05-16 EP claimed
US-20120101296-A1 METHOD FOR PREPARING TRICYCLIC DERIVATIVES JE IL PHARMACEUTICAL CO., LTD. (KR) 2012-04-26 US claimed
US-7696302-B2 High-molecular-weight polyazoles PBI PERFORMANCE PRODUCTS, INC. (US) 2010-04-13 US claimed
US-6960420-B2 Photosensitive resin composition, process for forming relief pattern, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS LTD (JP) 2005-11-01 US claimed
US-20040142275-A1 Photosensitive resin composition, process for forming relief pattern, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS LTD. (JP) 2004-07-22 US claimed
US-6420511-B1 SEPARATION AND PURIFICATION OF POLYESTERS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-07-16 US claimed
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN disclosed
WO-2025095106-A1 RESIST UNDERLAYER FILM FORMATION COMPOSITION 日産化学株式会社 2025-05-08 WO disclosed
US-20240319624-A1 RESIN PARTICLES, TONER, METHOD FOR MANUFACTURING RESIN PARTICLES, IMAGE FORMING APPARATUS, AND METHOD OF FORMING IMAGE RICOH COMPANY, LTD. (JP) 2024-09-26 US disclosed
EP-4174108-B1 RESIN PARTICLE, TONER, DEVELOPER, DEVELOPER STORAGE CONTAINER, RESIN PARTICLE PRODUCING METHOD, TONER PRODUCING METHOD, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH CO LTD (JP) 2024-09-18 EP disclosed
US-20240288789-A1 RESIN PARTICLE, TONER, DEVELOPING AGENT, DEVELOPING AGENT ACCOMMODATING UNIT, METHOD OF MANUFACTURING RESIN PARTICLE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2024-08-29 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed
US-6297351-B1 EXCELLENT IN ELECTRIC CHARACTERISTICS AND HEAT RESISTANCE, PRECURSOR FROM A DICARBOXYLIC ACID AND A BISAMINOPHENOL COMPOUND OR A DIAMINODIHYDROXY SUMITOMO BAKELITE COMPANY LIMITED (JP) 2001-10-02 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
US-6114497-A POLYBENOXAZOLE PRECURSOR HAVING RECURRING UNIT OF AROMATIC DICARBOXYLIC ACID AND 2,2'-BIS(3-AMINO-4-HYDROXY-5 OR 6-FLUOROALKYLSUBSTITUTED PHENYL)-TRIFLUOROMETHYLPHENYL)HEXAFLUOROPROPANE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2000-09-05 US disclosed
EP-0997488-A1 Polybenzoxazole resin and precursor thereof SUMITOMO BAKELITE COMPANY LIMITED (JP) 2000-05-03 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101296-A1 METHOD FOR PREPARING TRICYCLIC DERIVATIVES NISCH, CA3, CYP51A1 ALDH1A1 1514/4885ALB 3224/4885ALOX15 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.