Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415441 | 0.87 | TAS1R3 (0.67) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL2261220 | 0.86 | APLNR (0.65) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL10141758 | 0.86 | APLNR (0.65) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL22854464 | 0.84 | APLNR (0.63) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL2226834 | 0.84 | APLNR (0.63) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL20303137 | 0.84 | APLNR (0.63) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL15682813 | 0.84 | TAS1R3 (0.60) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL4259873 | 0.83 | APLNR (0.61) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| Hydrochloric Acid SCHEMBL22832267 | 0.83 | APLNR (0.61) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL14521439 | 0.83 | APLNR (0.61) | APLNRALDH1A1TAS1R3TAS1R1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185534-A | Preparation and application of 2, 4-dimethoxy benzyl urea compound | 济南大学 | 2021-07-30 | — | — | CN | claimed |
| CN-105503635-B | A kind of preparation method of the Dicarbonyl derivatives of 2 amido formacyl 1,3 | 苏州大学 | 2017-10-10 | — | — | CN | claimed |
| CN-113185534-A | Preparation and application of 2, 4-dimethoxy benzyl urea compound | 济南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-104781256-A | 3,4-disubstituted oxazolidinone derivatives and their use as inhibitors of the calcium activated potassium channel | HOFFMANN LA ROCHE | 2015-07-15 | — | — | CN | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |