Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360962 | 0.85 | DPP4 (0.41) | DPP4MAPKAPK2ALDH1A1GAA | |
| SCHEMBL3363973 | 0.82 | DPP4 (0.43) | DPP4MAPKAPK2 | |
| SCHEMBL3363369 | 0.81 | DPP4 (0.50) | DPP4MAPKAPK2 | |
| SCHEMBL3365213 | 0.79 | DPP4 (0.47) | DPP4 | |
| SCHEMBL3361886 | 0.78 | DPP4 (0.41) | DPP4 | |
| SCHEMBL3361995 | 0.78 | DPP4 (0.39) | DPP4PDE10A | |
| SCHEMBL3361880 | 0.78 | DPP4 (0.47) | DPP4PDE10A | |
| SCHEMBL3363284 | 0.77 | DPP4 (0.41) | DPP4MAPKAPK2ALDH1A1GAAPDE10A | |
| SCHEMBL3361923 | 0.76 | DPP4 (0.64) | DPP4 | |
| SCHEMBL3361983 | 0.75 | DPP4 (0.56) | DPP4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |